abstract：PURPOSE:To determine the neurologic outcome of patients with intracranial hypertension treated with barbiturate-induced coma. MATERIALS AND METHODS:The records of 49 patients who were admitted to a 31-bed medicosurgical intensive care unit over a 5-year period in whom a barbiturate coma was induced to control intracra...

journal_title：Journal of critical care

authors： Dereeper E,Berré J,Vandesteene A,Lefranc F,Vincent JL

更新日期：2002-03-01 00:00:00

abstract：PURPOSE:Increasingly, hospitals are engaging in continuous quality improvement (CQI) endeavors, aimed at optimizing patient care. Physician involvement is critical to the success of such initiatives. Little is known about any mediating factors that affect physician participation in these projects, though such knowledge...

journal_title：Journal of critical care

authors： Hill A,Gwadry-Sridhar F,Armstrong T,Sibbald WJ

更新日期：2001-12-01 00:00:00

abstract：PURPOSE:The Fas ligand (FasL)/Fas system is an apoptosis induction system that plays an important role in homeostasis and biophylaxis. We measured tumor necrosis factor alpha (TNF-alpha), soluble FasL (sFasL), and soluble Fas (sFas) in patients with acute hepatic failure to determine the relation between such failure a...

journal_title：Journal of critical care

authors： Nakae H,Narita K,Endo S

更新日期：2001-06-01 00:00:00

abstract：PURPOSE:The purpose of this article is to elucidate the effect of L-canavanine, a selective inhibitor of inducible NO synthase (iNOS), on hemodynamics, blood gas parameters, and plasma concentrations of lactate and endothelin-1 (ET-1) during endotoxic shock. MATERIALS AND METHODS:Eleven mongrel dogs under pentobarbita...

journal_title：Journal of critical care

authors： Mitaka C,Hirata Y,Yokoyama K,Imai T

更新日期：2001-03-01 00:00:00

abstract：PURPOSE:The purpose of this article was to determine the outcome, clinical and prognostic features, and microbiology of a large group of patients with community-acquired pneumonia (CAP) presenting in septic shock. MATERIALS AND METHODS:The placebo limb of the Norasept II database was examined. Data were collected on p...

journal_title：Journal of critical care

authors： Marik PE

更新日期：2000-09-01 00:00:00

abstract：PURPOSE:A volume challenge is useful for determining whether cardiac output will respond to further volume loading by the Frank-Starling mechanism. To properly test this mechanism, there must be an increase in right atrial pressure (Pra) but this requires variable amounts of normal saline. The purpose of this study was...

journal_title：Journal of critical care

authors： Magder S,Lagonidis D

更新日期：1999-12-01 00:00:00

abstract：PURPOSE:Dobutamine infusion is used to increase whole-body oxygen delivery in septic patients to satisfy unmet oxygen demand of hypoxic tissues. However, dobutamine infusion also increases myocardial work and myocardial oxygen consumption. Our goal was to determine the importance of this effect as a fraction of the inc...

journal_title：Journal of critical care

authors： Herbertson MJ,Russell JA,Walley KR

更新日期：1999-09-01 00:00:00

abstract：PURPOSE:The purpose of this study is to determine if monitoring urinary bladder PCO2, PO2, and calculated intramucosal pH would be a reliable index of tissue perfusion. MATERIALS AND METHODS:This nonrandomized controlled study was conducted in a laboratory at a university medical center. Eight immature female Yorkshir...

journal_title：Journal of critical care

authors： Lang JD Jr,Evans DJ,deFigueiredo LP,Hays S,Mathru M,Kramer GC

更新日期：1999-06-01 00:00:00

abstract：PURPOSE:Liquid perfluorochemicals reduce the production of reaction oxygen species by alveolar macrophages. We sought to determine whether the use of liquid perfluorochemicals in vivo during liquid ventilation would attenuate oxidative damage to the lung. MATERIALS AND METHODS:Healthy infant piglets (n = 16) were inst...

journal_title：Journal of critical care

authors： Steinhorn DM,Papo MC,Rotta AT,Aljada A,Fuhrman BP,Dandona P

更新日期：1999-03-01 00:00:00

abstract：PURPOSE:Thoracocardiography noninvasively monitors global stroke volume by inductive plethysmographic recording of ventricular volume curves as previously validated by thermodilution. Our purpose was to investigate the potential of thoracocardiography to individually assess stroke volume of the left ventricle. We hypot...

journal_title：Journal of critical care

authors： Bloch KE,Jugoon S,de Socarraz H,Manning K,Sackner MA

更新日期：1998-09-01 00:00:00

abstract：PURPOSE:Gastric intramucosal PCO2 (PiCO2) is a marker of splanchnic dysoxia and hypoperfusion that is increasingly used in intensive care medicine. We assessed two methods, saline-balloon tonometry versus continuous capnometric recirculating gas tonometry (CRGT), for detecting changes in PiCO2 in animals subjected to v...

journal_title：Journal of critical care

authors： Guzman JA,Kruse JA

更新日期：1998-06-01 00:00:00

abstract：PURPOSE:The purpose of this study is to examine the relationship between the occurrence of a difficult intubation and (1) the use of neuromuscular blocking agents (NMB) and (2) the presence of airway injuries. It is a retrospective analysis of data from a trauma registry. MATERIALS AND METHODS:Registry records of pati...

journal_title：Journal of critical care

authors： Vijayakumar E,Bosscher H,Renzi FP,Baker S,Heard SO

更新日期：1998-03-01 00:00:00

abstract：PURPOSE:The purpose of this article was to determine the extent to which patients at high risk of hospital death who undergo cardiopulmonary resuscitation (CPR) have previously had their life support preferences addressed and documented. MATERIALS AND METHODS:We conducted a retrospective chart review of all patients o...

journal_title：Journal of critical care

authors： Kernerman P,Cook DJ,Griffith LE

更新日期：1997-12-01 00:00:00

abstract：PURPOSE:During intracranial aneurysm surgery, numerous factors may alter cerebral blood flow and oxygen supply-demand balance. Continuous monitoring of jugular bulb venous oxygen saturation (SvjO2) may help in the anesthetic management of such procedures. MATERIALS AND METHODS:Fiberoptic SvjO2 was continuously monitor...

journal_title：Journal of critical care

authors： Clavier N,Schurando P,Raggueneau JL,Payen DM

更新日期：1997-09-01 00:00:00

abstract：INTRODUCTION:Barotrauma and cardiovascular insufficiency are frequently encountered problems in patients with acute bronchospastic disease who require mechanical ventilation. Permissive hypercapnia is a recognized strategy for minimizing these adverse effects; however, it has potential risks. Tracheal gas insufflation ...

journal_title：Journal of critical care

authors： Miro AM,Hoffman LA,Tasota FJ,Sigler DW,Gowski DT,Lutz J,Zullo T,Pinsky MR

更新日期：1997-03-01 00:00:00

abstract：:Sepsis and SIRS is the outward manifestation of a generalized uncontrolled inflammatory response, which, if sustained, induces widespread endothelial damage and MODS. Immunomodulating therapies, at present, have proven ineffective in reducing morbidity and mortality, presumably because of the heterogeneous nature of s...

journal_title：Journal of critical care

authors： Pinsky MR

更新日期：1996-06-01 00:00:00

abstract：PURPOSE:In the vascularly isolated canine hemidiaphragm, we tested the hypothesis that alpha-adrenoreceptor stimulation may influence diaphragmatic function and O2 extraction during reductions in O2 delivery (QO2di). METHODS:The diaphragm was perfused using a constant flow pump with blood diverted from the left femora...

journal_title：Journal of critical care

authors： Ward ME,Hussain SN

更新日期：1996-03-01 00:00:00

abstract：:Recent advances in the field of molecular biology have revolutionized our understanding of the functioning of living organisms and facilitated the development of robust tools for both diagnosis and treatment of diseases. With particular reference to the field of critical care medicine, development of molecular biology...

journal_title：Journal of critical care

authors： Downey GP,Waddell TK,Fukushima T,Sue-A-Quan A

更新日期：1995-09-01 00:00:00

abstract：PURPOSE:This study evaluates the use of transcranial Doppler (TCD) ultrasound in assessing the changes experienced by the cerebral circulation during cardiopulmonary resuscitation (CPR) and compares it with measurements of internal carotid artery (ICA) flow rates (ultrasonic flow-meter measurements) and cerebral blood ...

journal_title：Journal of critical care

authors： Lewis LM,Stothert JC Jr,Gomez CR,Ruoff BE,Hall IS,Chandel B,Standeven J

更新日期：1994-09-01 00:00:00

abstract：PURPOSE:The present study tested the hypothesis that scorpion sting induces left ventricular (LV) hypokinesia and myocardial ischemia shortly after injection due to reduction of coronary blood flow (CBF) and increased oxygen demand. METHODS:In 5 mechanically ventilated, open-chest dogs, we measured LV function followi...

journal_title：Journal of critical care

authors： Tarasiuk A,Sofer S,Huberfeld SI,Scharf SM

更新日期：1994-06-01 00:00:00

abstract：PURPOSE:Evaluation of the effects of nimodipine administration during and after cardiopulmonary resuscitation (CPR) on oxygen delivery and consumption was the aim of this study. METHODS:A randomized double-blind study in 32 anesthetized domestic pigs was performed. After 5 minutes of ventricular fibrillation (VF) and ...

journal_title：Journal of critical care

authors： Schindler I,Steltzer H,Weindlmayr-Goettel M,Steinbereithner K

更新日期：1994-03-01 00:00:00

abstract：:In this study, the physiological and metabolic effects of Carbicarb administered as an isotonic (150 mmol/L Na[n[]I+) or hypertonic (1 mol/L Na[n[]I+) solution over 2 minutes in the acidotic isolated heart were compared. Physiological monitoring as well as 31P and 23Na nuclear magnetic resonance spectroscopy were perf...

journal_title：Journal of critical care

authors： Huntley JJ,McCormack M,Jin H,Hutchison RB,Shapiro JI

更新日期：1993-12-01 00:00:00

abstract：:Sixty-nine patients undergoing liver transplantation were evaluated to elucidate the relationship between hypotension and physiological changes seen on reperfusion of the grafted liver. Measured variables included hemodynamic profiles, core temperature, serum potassium, ionized calcium levels, arterial blood-gas tensi...

journal_title：Journal of critical care

authors： Aggarwal S,Kang Y,Freeman JA,Fortunato FL Jr,Pinsky MR

更新日期：1993-09-01 00:00:00